The effect of musa acuminata stem in increasing macrophage and neovascular cells of healing process

Padjadjaran Journal of Dentistry

Retno Pudji Rahayu¹  Diah Savitri Ernawati¹  Maharani Laillyza Apriasari²  Dewi Puspitasari² 

[1] Airlangga University;Lambung Mangkurat University

关键词: Condensed tannin;    macrophage;    Musa acuminata;    neovascular;    terpenoid saponin.;   

DOI  :  10.24198/pjd.vol30no2.18324

学科分类：口腔科学

来源: Universitas Padjadjaran

【 摘 要 】

Introduction :Musa acuminatastem has both of imunostimulatory and imunosuppressant effects that are influenced by their concentrations. The study aimed to analyze the effect of Mauli banana stem extract (EMBS) to increase the number of macrophage and neovascular cells in traumatic ulcer healing.Methods : Rattus norvegicus of male Wistar strain  were used  as model of traumatic ulcer. The left buccal mucous was biopsied, then used the histopathology method to find the number of macrophage and neovascular cells.Results : EMBS gel was effected when administered at a concentration of 37.5% because it significantly increased the number of macrophage and neovascular cells in traumatic ulcer healing on the 3 rdday to 5 thdays.Conclusion :  It can be concluded that EMBS within concentration of 37.5% can accelerate ulcer healing through the increasing  number of macrophage and neovascular cells.

【 授权许可】

CC BY