Serum Biomarkers of Endothelial Dysfunction in Fabry Associated Cardiomyopathy

Frontiers in Cardiovascular Medicine

Jefferson Loso¹ 

关键词: matrix metalloproteinase 9;    angiostatins;    SDMA;    homoarginine;    Fabry disease;    Fabry cardiomyopathy;    vasculopathy;    endothelial dysfunction;   

DOI  :  10.3389/fcvm.2018.00108

学科分类：心脏病和心血管学

来源: Frontiers

【 摘 要 】

Background: Fabry disease (FD) is characterized by early development of vasculopathy and endothelial dysfunction. However, it is unclear whether these findings also play a pivotal role in cardiac manifestation. As Fabry cardiomyopathy (FC) is the leading cause of death in FD, we aimed to gather a better insight in pathological mechanisms of the disease.

【 授权许可】

CC BY