期刊论文详细信息
Global Advances in Health and Medicine
Sulforaphane from Broccoli Reduces Symptoms of Autism: A Follow-up Case Series from a Randomized Double-blind Study:
RhodaLynch1 
关键词: glucoraphanin;    isothiocyanate;    glucosinolate;    prevention;   
DOI  :  10.1177/2164957X17735826
学科分类:医学(综合)
来源: Sage Journals
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【 摘 要 】

IntroductionAutism spectrum disorder (ASD) affects 1 in 68 children, is characterized by impaired social interaction and communication as well as restricted or repetitive behaviors, and varies widely with respect to its causes and presentations. There are no validated pharmacologic treatments for the core symptoms of ASD. The social, medical, and economic burdens of ASD on families and caregivers are profound. We recently showed in a small clinical trial that sulforaphane (SF) from broccoli sprouts could significantly reduce the behavioral symptoms of ASD.MethodsAfter we completed the intervention phase of the original trial (2011–2013), many caregivers used over-the-counter dietary SF supplements in order to attempt to maintain improvements similar to those noted during the intervention. We periodically followed the progress of study participants through the summer of 2016.ResultsFamilies of 16 of the 26 subjects who received SF as part of the original study responded to requests for further information....

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