Prevalence of oral human papillomavirus (HPV) in the adult population of Córdoba, Argentina:

Translational Research in Oral Oncology

MICriscuolo¹ 

关键词: HPV infection;    healthy subjects;    tongue scrapings;    saliva;   

DOI  :  10.1177/2057178X18757334

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objective:To determine the prevalence of oral human papillomavirus (HPV) in the population of Córdoba, Argentina and its association with other risk factors.Methods:A sample of 401 volunteers over 18 years, representative of Cordoba city population, was selected. Using a questionnaire, we collected sociodemographic data including the use of tobacco, alcohol, and mate consumption. Two biological samples were taken from each individual, whole mouth saliva and a scraping of the posterior border of the tongue. HPV was determined by polymerase chain reaction using MY09/11 primers. Statistical associations were analyzed using χ2 test.Results:Prevalence of HPV in the population was of 3% (13/401). The mean age of HPV-positive cases was 42 years with a range of 20–85; 54% were females. Among the 13 cases whose saliva was positive for HPV, only 7 (54%) had HPV-DNA in the tongue scraping. All identified genotypes were of low risk and HPV11 was the most frequent type in 62% of positive cases. None of the positive su...

【 授权许可】

CC BY