Editorial: Pediatric Pulmonary Hypertension

Frontiers in Pediatrics

Maurice Beghetti¹ 

关键词: pediatrics;    pulmonary circulation;    pulmonary hypertension;    diagnostic tests;    routine;    therapeutics;   

DOI  :  10.3389/fped.2015.00105

学科分类：儿科学

来源: Frontiers

【 摘 要 】

Pulmonary hypertension (PH) can present at any age from the neonatal period to adulthood. Pediatric PH is similar to adults but differentiates itself as in a growing child the lungs are still developing (1). It is a hemodynamic condition defined by an increased pulmonary artery mean pressure above or equal to 25 mmHg (1). This can be associated with multiple clinical conditions forming different etiological groups with specific and diverse pathological and pathobiological characteristics (1). When implying an abnormal reduction of small pulmonary arteries section due to endothelial dysfunction, medial proliferation, and adventitial fibrosis, the disease is called pulmonary arterial hypertension (PAH). PAH induces typically a severe and devastating PH that leads to right heart failure and premature death.

【 授权许可】

CC BY