Rare case of subependymal giant cell astrocytoma without clinical features of tuberous sclerosis: Case report and literature review

Precision Radiation Oncology

Saumya Shukla¹  Mohammad Azam²  Rohini Khurana²  Satyajeet Rath²  Ruhi Parween³ 

[1] Dr Ram Manohar Lohia Institute of Medical Sciences Pathology Lucknow Uttar Pradesh India;Dr Ram Manohar Lohia Institute of Medical Sciences Radiation Oncology Lucknow Uttar Pradesh India;King George's Medical University Pediatrics Lucknow Uttar Pradesh India

关键词: radiotherapy;    subependymal giant cell astrocytoma;    tuberous sclerosis complex;   

DOI  :  10.1002/pro6.24

学科分类：医学（综合）

来源: Wiley

【 摘 要 】

Subependymal giant cell astrocytoma (SEGA) is a slow‐growing tumor originating in the walls of the lateral ventricles, usually presenting in the first two decades of life, and is often associated with tuberous sclerosis complex. However, few cases of SEGA without any clinical features of tuberous sclerosis complex have been reported. Here, we present a case of an 11‐year‐old boy with right hemibody weakness and headache for 1.5 years. He was diagnosed with solitary SEGA without any clinical features of tuberous sclerosis complex. Magnetic resonance imaging of the brain showed an intracranial space‐occupying lesion in the left internal capsule. Biopsy was consistent with SEGA. There were no stigmata of tuberous sclerosis complex. The patient was treated with curative intent by radiotherapy.

【 授权许可】

CC BY-NC-ND