Shorter Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia: The Experience of the Prospective, Randomized Brazilian GBTLI ALL-93 Protocol

Frontiers in Pediatrics

Silvia R. Br¹ 

关键词: childhood acute lymphoblastic leukemia;    maintenance ALL chemotherapy;    pediatric ALL survival in middle-low-income countries;   

DOI  :  10.3389/fped.2016.00110

学科分类：儿科学

来源: Frontiers

【 摘 要 】

AimMaintenance therapy is an important phase of the childhood ALL treatment, requiring 2-year long therapy adherence of the patients and families. Weekly methotrexate with daily 6-mercaptopurine (6MP) constitutes the backbone of maintenance therapy. Reduction in the maintenance therapy could overweight problems related with poverty of children with ALL living in limited-income countries (LIC).

【 授权许可】

CC BY