Precision regimen for personalized pancreatic cancer therapy

Precision Radiation Oncology

Xiaoli Zhang¹  Min Li²  Jinming Yu³ 

[1] Department of Medicine The University of Oklahoma Health Sciences Center Oklahoma City Oklahoma USA;Department of Radiation Oncology Shandong Cancer Hospital Affiliated to Shandong University Jinan Shandong China;Department of Surgery The University of Oklahoma Health Sciences Center Oklahoma City Oklahoma USA

关键词: pancreatic cancer;    precision medicine;   

DOI  :  10.1002/pro6.19

学科分类：医学（综合）

来源: Wiley

【 摘 要 】

Precision medicine could optimize the chemo‐ and radiotherapy strategies, and enhance the therapeutic efficiency, which might bring a promising outcome in the treatment of pancreatic cancer. Further understanding and discovery of new biomarkers combined with advanced imaging techniques could provide an accurate personalized treatment plan based on the diagnosis during the evolutionary stages of pancreatic cancer, and reduce the side‐effects found in traditional medicine, such as gemcitabine treatment. In the near future, with the accelerated development of precision medicine, this could be recommended as the first‐line therapeutic option in clinical management of pancreatic cancer. At the same time, more efforts should be focused on the personalized therapeutic regimens based on the specific pathological characteristics plus specific molecular features and genetic profiling of individual patients. Furthermore, the safety and efficacy of the individualized treatments should be further validated in clinical trials with enhanced applications.

【 授权许可】

CC BY-NC-ND