An overview of human handedness in twins

Frontiers in Psychology

Syuichi Ooki¹ 

关键词: twin study;    laterality;    handedness;    brain asymmetry;    zygosity;    monozygotic twins;    brain lateralization;    human behavior;   

DOI  :  10.3389/fpsyg.2014.00010

学科分类：心理学（综合）

来源: Frontiers

【 摘 要 】

There has been a long-standing debate on the complex correlation between the development of human hand preference and brain lateralization. Handedness, used as a proxy for cerebral lateralization, is a topic of considerable importance because of its potential to reveal the mechanisms of the underlying pathophysiology of problems related to brain development or cognitive systems. Twin studies, which represent an important method of research in human genetics, would provide valuable suggestions to the studies on the relationship between lateralization and cognitive systems. Many studies have been performed using twin subjects; however, the results are inconsistent, partly because of sample size, background assumptions, data limits or inaccuracies, incorrect zygosity classification, and/or lack of birth histories. In summary, within the long history and large number of twin studies performed on handedness, a surprisingly large number of controversial findings have been reported, suggesting the complicated nature of this phenotype. In this mini review, the wide variety of twin studies on human handedness performed to date are introduced.

【 授权许可】

CC BY