Polyphenolic Content, Antioxidant and Antimicrobial Activities of Vernonia mespilifolia Less. Used in Folk Medicine in the Eastern Cape Province, South Africa:

Journal of Evidence-Based Integrative Medicine

Jeremiah OshiomameUnuofin¹ 

关键词: agar dilution;    antimicrobial activity;    Vernonia mespilifolia;    polyphenolic contents;    radical scavenging activity;   

DOI  :  10.1177/2515690X18773990

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Vernonia mespilifolia Less. is a shrub of the Asteraceae family used in the South African traditional medicine system for the management of weight loss, hypertension, and heartwater disease. There is a need for scientific evaluation to validate its ethnomedicinal usage. In vitro assays were conducted to evaluate the polyphenolic content, antioxidant and antimicrobial properties of different solvent extracts (acetone, aqueous, and ethanol) of the whole plant of Vernonia mespilifolia spectrophotometric and agar dilution techniques, respectively. The result revealed varying amounts of polyphenolics in the different solvent extracts corresponding to the antioxidant activities. Also, only the acetone and ethanol extracts inhibited the growth of the selected bacteria and fungi. These findings reveal that the extracts have strong bioactive compounds and hence support its ethnomedicinal application.

【 授权许可】

CC BY-NC