Termination of SUNCT with intravenous lignocaine followed by oral mexiletine:

Cephalalgia Reports

EoinMulroy¹ 

关键词: headache;    lignocaine;    mexiletine;    neuralgia;    trigeminal autonomic cephalalgias;   

DOI  :  10.1177/2515816318768827

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Background:The trigeminal autonomic cephalalgias (TACs) are a group of debilitating, pathophysiologically similar headache syndromes characterized by facial pain and autonomic symptoms in areas supplied by the trigeminal nerve. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is among the rarest of the TAC syndromes and can be particularly recalcitrant to treatment.Case:We describe the case of a 50-year old woman with difficult-to-control SUNCT whose pain was completely aborted within hours of commencing intravenous lignocaine therapy and was maintained pain-free after transitioning to oral mexiletine.Conclusion:This is the first report of successful transition from intravenous lignocaine to oral mexiletine in SUNCT, and we suggest that this treatment should be tried early in difficult-to-control SUNCT. This therapy is safe, effective and with minimal side effects if administered in an appropriate manner.

【 授权许可】

CC BY