Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension:

Pulmonary Circulation

MitsushigeMurata¹ 

关键词: riociguat;    right ventricular contraction;    pulmonary hypertension;   

DOI  :  10.1177/2045893217746111

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.

【 授权许可】

CC BY