期刊论文详细信息
Global Pediatric Health | |
Early Risk Factors of Moderate/Severe Hepatotoxicity After Suicide Attempts With Acetaminophen in 11- to 15-Year-Old Children: | |
Rikke LindgaardHedeland1  | |
关键词: hepatotoxicity; acetaminophen; suicide attempt; early risk factors of hepatotoxicity; | |
DOI : 10.1177/2333794X14552897 | |
学科分类:医学(综合) | |
来源: Sage Journals | |
【 摘 要 】
Objective. To characterize early risk factors of moderate/severe hepatotoxicity in a pediatric population with acetaminophen overdose, due to suicide attempt, admitted to a general secondary-level pediatric department. Methods. A retrospective case study of 107 patients, 11 to 15 years old. Results. There was a highly significant relationship between the number of episodes of prehospital vomiting and several elevated hepatologically relevant biochemical parameters, for example, maximum aspartate aminotransferase (P = .0001). The duration of the latency time before initiation of N-acetylcysteine treatment was significantly related to the elevation of several hepatologically relevant biochemical parameters (eg, maximum γ-glutamyl transferase; P = .0001). Patients suffering from illness prior to their suicide attempt had significantly greater elevations of their hepatologically relevant biochemical parameters, for example, maximum alanine aminotransferase (P = .01) levels than healthy patients. Conclusion. B...【 授权许可】
CC BY
【 预 览 】
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RO201904020874780ZK.pdf | 497KB | download |