Professor Krystyna Kotełko and her contribution to the study of Proteus endotoxin:

Innate Immunity

Antoni WRóżalski¹ 

关键词: Prof Krystyna Kotełko;    Proteus bacteria;    uropathogen;    endotoxin;    lipopolysaccharide;   

DOI  :  10.1177/1753425918763066

学科分类：生物科学（综合）

来源: Sage Journals

【 摘 要 】

Professor Krystyna Kotełko was working as a microbiologist at the University of Łódź (Poland). Her main object of study was the LPS (endotoxin) of opportunistic urinary pathogens from the genus Proteus. She demonstrated, for the first time, the presence of uronic acids and amino acids, as well as two heptoses (L-glycero-D-manno-heptose and D-glycero-D-manno-heptose) and hexosamines in Proteus LPS, and developed a classification scheme of the Proteus LPS into chemotypes. Prof Kotełko also initiated studies on the chemical structure of Proteus O-specific polysaccharide and investigations on the serological specificity of this part of LPS, as well its core region. She also analysed the virulence factors of these bacteria, such as haemolysin and invasiveness.

【 授权许可】

CC BY