Метаболические механизмы хемилюминесцентной активности нейтрофильных гранулоцитов у квалифицированных спортсменов

Acta Biomedica Scientifica

И. И. Гвоздев¹  А. А. Савченко²  К. П. Базарин² 

[1] ФГАОУ ВПО «Сибирский федеральный университет»;ФГБНУ «НИИ медицинских проблем Севера»

关键词: нейтрофилы;    метаболизм;    функциональная активность;    физическая нагрузка;   

DOI  :  

学科分类：自然科学（综合）

来源: Scientific entre for Family Health and Human Reproduction Problems

【 摘 要 】

The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanisms and researching the methods for its correction. 51 male athletes of 22,1 ± 3,7 y. o. and 64 healthy males of the same age as the reference group were participated in the study. We found that metabolic resources providing the intensity of respiratory burst depend on mitochondrial processes condition and lipid metabolism. The activation index has logarithmic dependence on NAD(P)-MDH, NAD-MDH, NAD-IDH activities. Therefore the functional activity of neutrophilic granulocytes in athletes has positive correlation with plastic exchange level and negative correlation with oxygen-depended ATP production.

【 授权许可】

CC BY