Tryptophan and purine metabolites are consistently upregulated in the urinary metabolome of patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 2

卷:468

Law, Kai P. ; Han, Ting-Li ; Mao, Xun ; Zhang, Hua

关键词: Gestational diabetes;    Urine;    Longitudinal study;    Multilevel analysis;    Tryptophan metabolism;    Purine metabolism;    Metabolomics;   

DOI  :  10.1016/j.cca.2017.02.018

学科分类：内分泌与代谢学

【 摘 要 】

Background: Gestational diabetes mellitus (GDM) is a pathological state of glucose intolerance associated with adverse pregnancy outcomes and an increased risk of developing maternal type 2 diabetes later in life. The mechanisms underlying GDM development