The Metabolite Profiles of the Obese Population Are Gender-Dependent

卷:13

Xie, Guoxiang ; Ma, Xiaojing ; Zhao, Aihua ; Wang, Congrong ; Zhang, Yinan ; Nieman, David ; Nichoson, Jeremy K. ; Jia, Wei ; Bao, Yuqian ; Jia, Weiping

关键词: obesity;    metabonomics;    branched-chain amino acid;    insulin resistance;    gender;    UPLC-MS;    GC-MS;   

DOI  :  10.1021/pr500434s

学科分类：内分泌与代谢学

【 摘 要 】

Studies have identified that several amino acids, in particular, branched-chain amino acids (BCAAs), have increased significantly in obese individuals when compared to lean individuals. Additionally, these metabolites were strongly associated with future