Polymorphism on chromosome 9p21.3 contributes to early-onset and severity of coronary artery disease in non-diabetic and type 2 diabetic patients

卷:124

Wang Wei ; Peng Wen-hui ; Lu Lin ; Zhang Rui-yan ; Zhang Qi ; Wang Ling-jie ; Chen Qiu-jing ; Shen Wei-feng

关键词: coronary artery disease;    type 2 diabetes mellitus;    single nucleotide polymorphism;    chromosome 9p21.3;   

DOI  :  10.3760/cma.j.issn.0366-6999.2011.01.013

学科分类：内分泌与代谢学

【 摘 要 】

Background Susceptibility to coronary artery disease (CAD) and diabetes is encoded by distinct, tightly-linked single nucleotide polymorphisms on chromosome 9p21. This study aimed to examine the association of variant rs1333049 on chromosome 9p21.3 with e