Metabonomic Variations in the Drug-Treated Type 2 Diabetes Mellitus Patients and Healthy Volunteers

卷:8

Bao, Yuqian ; Zhao, Tie ; Wang, Xiaoyan ; Qiu, Yunping ; Su, Mingming ; Jia, Weiping ; Jia, Wei

关键词: metabonomics;    Type 2 diabetes mellitus;    repaglinide;    metformin;    rosiglitazone;    gas chromatography/mass spectrometry;   

DOI  :  10.1021/pr800643w

学科分类：内分泌与代谢学

【 摘 要 】

The pathological development and the drug intervention of type 2 diabetes mellitus (T2DM) involve altered expression of downstream low molecular weight metabolites including lipids and amino acids, and carbohydrates such as glucose. Currently, a small num