Effects and pharmacokinetics of oral glibenclamide and glipizide in Caucasian and Chinese patients with type-2 diabetes

卷:56

Jonsson, A ; Chan, JCN ; Rydberg, T ; Vaaler, S ; Hallengren, B ; Cockram, CS ; Critchley, JAJH ; Melander, A

关键词: sulphonylurea;    proinsulin;    pharmacokinetics;   

DOI  :  10.1007/s002280000214

学科分类：内分泌与代谢学

【 摘 要 】

The effects and kinetics of oral glibenclamide (Gb) and glipizide (Gz) were studied in Caucasian and Chinese patients (ten in each group) with type-2 diabetes. In randomised order, 2.5 mg Gb, 2.5 mg Gz or placebo was given orally before the administration