期刊论文详细信息
卷:69 | |
Effect of CYP2C9 and SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of nateglinide in healthy Chinese male volunteers | |
Cheng, Yu ; Wang, Guo ; Zhang, Wei ; Fan, Lan ; Chen, Yao ; Zhou, Hong-Hao | |
关键词: Nateglinide; CYP2C9 polymorphism; SLCO1B1 polymorphism; OATP1B1; Pharmacogenetics; | |
DOI : 10.1007/s00228-012-1364-9 | |
学科分类:内分泌与代谢学 | |
【 摘 要 】
Purpose Nateglinide is commonly used in the treatment of patients with type 2 diabetes mellitus. Our objective was to assess the association between CYP2C9 and SLCO1B1 polymorphisms and the metabolism of nateglinide in healthy Chinese male volunteers. Met
【 授权许可】
【 预 览 】
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Cheng-2013-Effect of CYP2C9 and SLCO1B1 polymo.pdf | KB | download |