Association of IL-10 gene (-1082A > G,-819C > T and-592C > A) polymorphism and its serum level with metabolic syndrome of north Indian subjects

卷:96

Madeshiya, Amit Kumar ; Singh, Shraddha ; Dwivedi, Shipra ; Konwar, Rituraj ; Natu, Shankar Madhav ; Ghatak, Ashim

关键词: metabolic syndrome;    insulin resistance;    homeostasis model assessment-insulin resistance;    IL-10 gene;    polymorphism;   

DOI  :  10.1007/s12041-016-0738-7

学科分类：内分泌与代谢学

【 摘 要 】

Metabolic syndrome (MetS) is an inflammatory disorder, in which various cytokines play important role in tilting balance towards disease state. Interleukin-10 (IL-10) is an important antiinflammatory cytokine, but its genetic polymorphisms and serum level