5-Alkylpyrrole-2-carboxaldehyde derivatives from the Chinese sponge Mycale lissochela and their PTP1B inhibitory activities

卷:28

Xue, Duo-Qing ; Liu, Hai-Li ; Chen, Si-Han ; Mollo, Ernesto ; Gavagnin, Margherita ; Li, Jia ; Li, Xu-Wen ; Guo, Yue-Wei

关键词: 5-Alkylpyrrole-2-carboxaldehyde;    Sponge;    Mycale lissochela;    PTP1B inhibitor;    Marine natural product;   

DOI  :  10.1016/j.cclet.2017.03.040

学科分类：内分泌与代谢学

【 摘 要 】

Two new 5-alkylpyrrole-2-carboxaldehyde derivatives, mycalenitrile-15 (1) and mycalenitrile-16 (2), along with five known related ones (3-7), were isolated from the South China Sea sponge Mycale lissochela. The structures of the new compounds were elucida