Phenolic profiles of 20 Canadian lentil cultivars and their contribution to antioxidant activity and inhibitory effects on alpha-glucosidase and pancreatic lipase

卷:172

Zhang, Bing ; Deng, Zeyuan ; Ramdath, D. Dan ; Tang, Yao ; Chen, Peter X. ; Liu, Ronghua ; Liu, Qiang ; Tsao, Rong

关键词: Lentils;    Phenolics;    Antioxidant activities;    alpha-Glucosidase;    Lipase;    Weight loss;    Diabetes;   

DOI  :  10.1016/j.foodchem.2014.09.144

学科分类：食品科学和技术

【 摘 要 】

Phenolic extracts from 20 Canadian lentil cultivars (Lens culinaris) were evaluated for total phenolic contents and composition, antioxidant activities (DPPH, FRAP, ORAC), and inhibitory properties against alpha-glucosidase and pancreatic lipase. Twenty one phenolic compounds were identified in the present study, with the majority being flavonoids, including kaempeferol glycosides, catechin/epicatechin glucosides and procyanidins. These phenolic compounds not only contributed significantly to the antioxidant activities, but they were also good inhibitors of alpha-glucosidase and lipase, two enzymes, respectively, associated with glucose and lipid digestion in the human intestine, thus contributing significantly to the control of blood glucose levels and obesity. More interestingly, it was the flavonols, not the flavanols, which showed the inhibitory activities against alpha-glucosidase and pancreatic lipase. Our result provides supporting information for developing lentil cultivars and functional foods with improved health benefits and suggests a potential role of lentil consumption in managing weight and control of blood glucose. (C) 2014 Published by Elsevier Ltd.