Risk for self-reported anorexia or bulimia nervosa based on drive for thinness and negative affect clusters/dimensions during adolescence: A three-year prospective study of the TChAD cohort

卷:48

Penas-Lledo, Eva ; Bulik, Cynthia M. ; Lichtenstein, Paul ; Larsson, Henrik ; Baker, Jessica H.

关键词: drive for thinness;    anxiety;    depression;    negative affect;    subtyping;    eating disorders;    anorexia;    bulimia;    risk;   

DOI  :  10.1002/eat.22431

学科分类：食品科学和技术

【 摘 要 】

ObjectiveThis study explored the cross-sectional and predictive effect of drive for thinness and/or negative affect scores on the development of self-reported anorexia nervosa (AN) and bulimia nervosa (BN). MethodK-means were used to cluster the Eating Disorder Inventory-Drive for Thinness (DT) and Child Behavior Checklist Anxious/Depressed (A/D) scores from 615 unrelated female twins at age 16-17. Logistic regressions were used to assess the effect of these clusters on self-reported eating disorder diagnosis at ages 16-17 (n=565) and 19-20 (n=451). ResultsDT and A/D scores were grouped into four clusters: Mild (scores lower than 90th percentile on both scales), DT (higher scores only on DT), A/D (higher scores only on A/D), and DT-A/D (higher scores on both the DT and A/D scales). DT and DT-A/D clusters at age 16-17 were associated cross-sectionally with AN and both cross-sectionally and longitudinally with BN. The DT-A/D cluster had the highest prevalence of AN at follow-up compared with all other clusters. Similarly, an interaction was observed between DT and A/D that predicted risk for AN. DiscussionHaving elevated DT and A/D scores may increase risk for eating disorder symptomatology above and beyond a high score on either alone. Findings suggest that cluster modeling based on DT and A/D may be useful to inform novel and useful intervention strategies for AN and BN in adolescents. (c) 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:692-699)