Fat may affect magnetic resonance signal intensity and brain tissue volumes

卷:10

Mon, Anderson ; Abe, Christoph ; Durazzo, Timothy C. ; Meyerhoff, Dieter J.

Koforidua Polytech

关键词: Fat;    Magnetic resonance signal hypo-intensity;    Grey matter;    White matter;    Obesity;   

DOI  :  10.1016/j.orcp.2015.07.009

学科分类：食品科学和技术

【 摘 要 】

Obesity/overweight is reported to affect MR-measured brain tissue volume and white matter (WM) signal intensity. This study investigated possible effects of fat on these measures, using pig fat on three participants at a 4 T magnet. Grey matter volumes in the presence of fat were lower than baseline measures. Total WM volumes in the presence of fat were higher than baseline measures. WM hypointensities on T1-weighted images were higher in the presence of fat than baseline measures. Therefore physical effects of head fat of obese/overweight individual may at least, partly contribute to the association of obesity/overweight with MR structural measures. (C) 2015 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.