Polyphenols, antioxidants, and antimutagenic effects of Copaifera langsdorffii fruit

卷:197

Batista, Angela Giovana ; Ferrari, Angelica Simoes ; da Cunha, Debora Cristina ; da Silva, Juliana Kelly ; Betim Cazarin, Cinthia Bau ; Correa, Luiz Claudio ; Prado, Marcelo Alexandre ; de Carvalho-Silva, Luciano Bruno ; Esteves, Elizabethe Adriana ; Marostica Junior, Mario Roberto

Dept Alimentos & Nutr

关键词: Copaiba;    Gallic acid;    Micronuclei;    Antioxidant capacity;   

DOI  :  10.1016/j.foodchem.2015.11.093

学科分类：食品科学和技术

【 摘 要 】

Copaifera langsdorffii (copaiba) is a Brazilian exotic fruit, poorly studied regarding its bioactive composition. The aim of this study was to determine bioactive compounds, antioxidant and antimutagenic activities of copaiba pulp. The samples were extracted with different solvents in order to analyze polyphenol compounds (Folin Ciocalteau and HPLC-DAD), total flavonoids (reaction with AlCl3) and antioxidant capacity (FRAP, ORAC, DPPH). The copaiba fruit showed high polyphenol content and antioxidant capacity. Phenolic compounds, such as gallic acid, epicatechin gallate, catechin, epicatechin and isoquercitrin, were identified in the copaiba pulp. Despite the antioxidant capacity, the highest dose of copaiba showed no antimutagenic effects in the in vivo study. The dose which showed antimutagenic activity was 100 mg kg(-1). (C) 2015 Published by Elsevier Ltd.