期刊论文详细信息
卷:146 | |
Prolonged Exclusive Breastfeeding Duration Is Positively Associated with Risk of Anemia in Infants Aged 12 Months | |
Wang, Fenglei ; Liu, Huijuan ; Wan, Yi ; Li, Jing ; Chen, Yu ; Zheng, Jusheng ; Huang, Tao ; Li, Duo | |
Zhejiang Univ | |
关键词: anemia; children; cohort; exclusive breastfeeding duration; infants; | |
DOI : 10.3945/jn.116.232967 | |
学科分类:食品科学和技术 | |
【 摘 要 】
Background: The association between exclusive breastfeeding duration and infant anemia is not clear. Objective: This study aimed to assess the association of exclusive breastfeeding duration with risk of anemia in infants at 12 mo of age and in children aged 48-71 mo in mainland China. Methods: Detailed breastfeeding information and anthropometric data were obtained for 65,256 children enrolled in the Jiaxing Birth Cohort at 1, 3, and 6 mo of age. Hemoglobin was measured in 25,549 children at 12 mo and in 32,770 children between the ages of 48 and 71 mo. Anemia was defined as hemoglobin concentrations <110 g/L in children aged <60 mo and <115 g/L in children aged >= 60 mo. The associations between exclusive breastfeeding duration and risk of anemia were assessed as adjusted ORs by using multiple logistic regression. Results: Overall anemia prevalences at 12 and 48-71 mo were 24.9% and 9.9%, respectively. Exclusive breastfeeding for >= 6 mo, but not for 3-5 mo, was significantly associated with a higher risk of anemia in infants at age 12 mo (OR: 1.15; 95% CI: 1.02, 1.29; P=0.02) compared with exclusive breastfeeding for <3 mo. For young children aged 48-71 mo, this finding was only marginally significant (OR: 1.13; 95% CI: 0.99, 1.29; P = 0.08). Prolonged duration of exclusive breastfeeding was also significantly associated with decreased hemoglobin concentrations of -0.56 g/L (95% CI: -1.10, -0.03; P= 0.04) in infants and -0.99 g/L (95% CI: -1.44, -0.55; P< 0.001) in young children. Conclusions: Exclusive breastfeeding for >= 6 mo was associated with an increased risk of anemia in infants aged 12 mo and with lower hemoglobin concentrations in both infants aged 12 mo and young children aged 48-71 mo. Parents should provide infants with an adequate source of iron after 6 mo of exclusive breastfeeding.【 授权许可】
【 预 览 】
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