Comparative proteomics of milk fat globule membrane in goat colostrum and mature milk

卷:209

Lu, Jing ; Liu, Lu ; Pang, Xiaoyang ; Zhang, Shuwen ; Jia, Zhenhu ; Ma, Changlu ; Zhao, Lili ; Lv, Jiaping

Chinese Acad Agr Sci

关键词: Goat MFGM;    Colostrum;    Mature milk;    Acute phase response proteins;    Long term depression;   

DOI  :  10.1016/j.foodchem.2016.04.020

学科分类：食品科学和技术

【 摘 要 】

As an important nutrient source in large area of world, the composition and nutritional value of goat milk are not well deliberated. Detailed annotation of protein composition is essential to address the physiological and nutritional value of goat milk. In the present study, 423 colostrum and mature goat milk fat globule membrane (MFGM) proteins were identified. The abundance of 189 proteins was significantly different between colostrums and mature milk MFGM. The acute phase proteins were higher in colostrums MFGM than those in mature milk MFGM which protected newborns at the beginning of life. Proteins related to synthesis and secretion were conserved through lactation to ensure the milk production. Of note, long term depression (LTD) proteins were observed in colostrum and mature milk MFGM. Milk LTD proteins could be potential biomarkers for diagnosis of lactation related depressive syndromes and should be taken into considerations of their effects on newborns. (C) 2016 Elsevier Ltd. All rights reserved.