Monoterpenoids from the traditional North Italian vegetable Aruncus dioicus (Walter) Fernald var. vulgaris (Maxim.) H. Hara (Rosaceae)

卷:221

Granica, Sebastian ; Fusani, Pietro ; Stanislawska, Iwona ; Piwowarski, Jakub P. ; Melck, Dominique ; Motta, Andrea ; Zidorn, Christian

Christian Albrechts Univ Kiel

关键词: Aruncus dioicus var. vulgaris;    Aruncus dioicus var. aethusifolius;    Rosaceae;    Buck's beard;    Monoterpenoids;    Vegetables from the wild;    Chemosystematics;    Plant bioactives;   

DOI  :  10.1016/j.foodchem.2016.10.090

学科分类：食品科学和技术

【 摘 要 】

Investigations of young shoots of Aruncus dioicus (Walter) Fernald var. vulgaris (Maxim.) H. Hara (Rosaceae), collected from the wild and used as vegetables in alpine provinces of Italy, yielded eight monoterpenoids. Besides known compounds, aruncin A, aruncide A, and cimicifugolide, five previously undescribed substances, aruncins C, D, and E, and aruncides D and E, were identified. Based on results from the full synthesis of aruncin B, structures of aruncin A and aruncide A were revised. Structures were established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy and based on data from synthetic aruncin B. An HPLC-DAD-ESI-MS method was developed to investigate the distribution of the monoterpenoids in different organs of Aruncus dioicus var. vulgaris and in aerial parts of A. dioicus var. aethusifolius (H. Lev.) H. Hara [Syn.: Aruncus aethusifolius (H. Lev.) Nakai]. Preliminary bioactivity studies moreover indicated weak cytotoxicity for some of the compounds against human prostrate adenocarcinoma cells. (C) 2016 Elsevier Ltd. All rights reserved.