Alanine with the Precipitate of Tomato Juice Administered to Rats Enhances the Reduction in Blood Ethanol Levels

Journal of nutrition and metabolism

Sachie Shiiya¹  Yoshimi Tokumaru¹  Tomomasa Kanda¹  Shunji Oshima¹ 

[1] Research & Development Laboratories for Innovation, Asahi Group Holdings, Ltd., Ibaraki 302-0106, Japan, asahigroup-holdings.com

DOI  :  10.1155/2015/280781

学科分类：内分泌与代谢学

来源: Hindawi Publishing Corporation

【 摘 要 】

Delay in gastric emptying (GE) lowers the blood ethanol concentration (BEC) after alcohol administration. We previously demonstrated that water-insoluble fractions, mainly comprising dietary fiber derived from many types of botanical foods, possessed the ability to absorb ethanol-containing aqueous solutions. Furthermore, there was a significant correlation between the absorption of ethanol and lowering of BEC because of delay in GE. Here we identified dietary nutrients that synergize with the water-insoluble fraction of tomatoes to lower BEC in rats. Consequently, unlike tomato juice without alanine, tomato juice with 5.0% alanine decreased BEC depending on the delay in GE and mediated the ethanol-induced decrease in the spontaneous motor activity (an indicator of drunkenness). Our findings indicate that the synergism between tomato juice and alanine to reduce the absorption of ethanol was attributable to the effect of alanine on precipitates such as the water-insoluble fraction of tomatoes.

【 授权许可】

CC BY