Antioxidant and Antiradical Properties of Selected Flavonoids and Phenolic Compounds

Biochemistry research international

?ükrü Beydemir¹  Zübeyir Huyut²  ?lhami Gülçin³ 

[1] Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26210 Eski?ehir, Turkey, anadolu.edu.tr;Department of Biochemistry, Medical Faculty, Yuzuncu Y?l University, 65080 Van, Turkey, yyu.edu.tr;Department of Chemistry, Faculty of Sciences, Atatürk University, 25240 Erzurum, Turkey, atauni.edu.tr

DOI  :  10.1155/2017/7616791

学科分类：生物化学/生物物理

来源: Hindawi Publishing Corporation

【 摘 要 】

Phenolic compounds and flavonoids are known by their antioxidant properties and one of the most important sources for humans is the diet. Due to the harmful effects of synthetic antioxidants such as BHA and BHT, natural novel antioxidants have become the focus of attention for protecting foods and beverages and reducing oxidative stress in vivo. In the current study, we investigated the total antioxidant, metal chelating, Fe3+ and Cu2+ reduction, and free radical scavenging activities of some phenolic and flavonoid compounds including malvin, oenin, ID-8, silychristin, callistephin, pelargonin, 3,4-dihydroxy-5-methoxybenzoic acid, 2,4,6-trihydroxybenzaldehyde, and arachidonoyl dopamine. The antioxidant properties of these compounds at different concentrations (10–30??g/mL) were compared with those of reference antioxidants such as BHA, BHT, ?-tocopherol, and trolox. Each substance showed dose-dependent antioxidant activity. Furthermore, oenin, malvin, arachidonoyl dopamine, callistephin, silychristin, and 3,4-dihydroxy-5-methoxybenzoic acid exhibited more effective antioxidant activity than that observed for the reference antioxidants. These results suggest that these novel compounds may function to protect foods and medicines and to reduce oxidative stress in vivo.

【 授权许可】

CC BY