Síndrome de Behcet

Revista Cubana de Hematología, Inmunología y Hemoterapia

Alfonso Valdés, María Elena¹ 

[1] Instituto de Hematología e Inmunología, La Habana, Cuba

关键词: Behcet;    ocular ulcers;    genital ulcers;    arthritis;    vasculitis.;   

DOI  :  

学科分类：生理学与病理学

来源: SciELO

【 摘 要 】

Behcet's syndrome, also known as Behcet's disease is a chronic autoinflammatory process of low frequency and unknown etiology. It is a vasculitis affecting arteries and veins of all sizes that causes an alteration of endothelial function and is expressed clinically by organ damage at various levels. It has a higher incidence in countries located in the ancient Silk Road (East Mediterranean, Middle East and East Asia). Its pathogenesis involves genetic, microbial and immunological factors.Symptoms vary from person to person and according to geographical regions, but the most common are oral and genital ulcers, eye inflammation (uveitis, iritis and retinitis), skin lesions and arthritis. In some cases they can present central nervous system, gastrointestinal tract and kidney. As a guide to the diagnosis criteria of International Study Group of Behcet's disease are used. Treatment includes topical and systemic drugs. The most commonly used are steroids, tumor necrosis factor inhibitors and immunosuppressants.

【 授权许可】

CC BY-NC-SA