Capsular serotypes, virulence-associated genes and antimicrobialsusceptibility of Streptococcus suis isolates from pigs inKorea

The Journal of Veterinary Medical Science

Sang-Ik OH¹  Jong Wan KIM¹  Jae-Won BYUN¹  Byeong-Yeal JUNG¹  Marcelo GOTTSCHALK¹  Ha-Young KIM¹  Albert Byungyun JEON²  Aeran KIM³ 

[1] Animal Disease Diagnostic Division, Animal and PlantQuarantine Agency, 177 Hyeoksin 8-ro, Gimcheon, 39660, Korea;College of Veterinary Medicine, Chonbuk NationalUniversity, 79 Gobong-ro, Iksan, 54596, Korea;Department of Pathology and Microbiology, Faculty ofVeterinary Medicine, University of Montréal, St-Hyacinthe, Québec, J2S 2M2,Canada

关键词: antimicrobial susceptibility;    clonal complex;    serotype;    Streptococcus suis;    virulence-associated gene;   

DOI  :  10.1292/jvms.16-0514

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Streptococcus suis is an important pig pathogen with potential for humantransmission. The serotype distributions and phenotypic characteristics vary over time andamong regions; however, little is known about the characteristics of S.suis isolates in Korea. In this study, 240 S. suis isolatescollected from pigs in Korea in 2009–2010 were serotyped by coagglutination tests,subsequently screened for three virulence-associated genes (mrp,epf and sly) and tested for antimicrobialsusceptibility. As for 80 isolates, the serotypes of which were relevant to humaninfections, clonal complexes (CCs) were further identified by PCR. Serotype 3 was the mostprevalent (15.8%), followed by serotype 2 (15.0%), with geographical variation for eachserotype. Overall, 55.4% of the isolates carried mrp, whereas only 3.8%carried epf. CC25 was the most prevalent (41.3%) and was related toserotypes 2 and 9. The isolates showed higher susceptibility to ampicillin (93.4%) andceftiofur (90.8%) than to the other antimicrobial agents tested. The highest resistancerate was observed to tetracycline (98.0%), followed by erythromycin (88.8%). In addition,the resistance to certain antimicrobials was significantly associated, in part, withvirulence-associated genes or serotypes. Therefore, continuous characterization ofS. suis is essential for the benefit of veterinary and humanmedicine.

【 授权许可】

Unknown