Leader for DB “Developmental Gene Regulatory Networks” Collection

Developmental biology

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DOI  :  10.1016/j.ydbio.2010.03.020

学科分类：生物科学（综合）

来源: Academic Press

【 摘 要 】

Following is a small, eclectic selection of papers on the theme of Gene Regulatory Networks for Development, published in special recognition of the 50th Anniversary of the founding of this Journal, which occurred in 1959. This prompts reflection on the almost inconceivable intellectual distance that separates the developmental biology of 1959 from that here represented. In 1959, when I was a second year graduate student, developmental biology was a largely nucleus- and gene-free area of experiment and observation; it was focused to a great extent on entirely undefined signaling factors and their effects on regional embryonic fates; on (semi-relevant) biophysical processes, on bioenergetics; on shapes; on description and more description of developmental processes. There was little logic and hardly any molecular biology in development. There were to be sure some few exceptional scientists whose minds were of a much more forward cast, several of whom I was lucky enough to meet. They, such as Jean Brachet and Jack Schultz.

【 授权许可】

CC BY