Diffusion kurtosis imaging of gliomas grades II and III - a study of perilesional tumor infiltration, tumor grades and subtypes at clinical presentation

Radiology and Oncology

Markus Nilsson¹  Danielle van Westen²  Anna F. Delgado³  Jimmy Lätt⁴  Sylwia Libard⁵  Irina Alafuzoff⁵  Shala G. Berntsson⁶  Anja Smits⁶  Maria Zetterling⁷  Markus Fahlström⁸  Elna-Marie Larsson⁸ 

[1] Bioimaging Center, Lund University, Lund, SwedenOther articles by this author:;Clinical Sciences Lund, Diagnostic Radiology, Lund University, Lund, SwedenOther articles by this author:;Corresponding authorDepartment of Surgical Sciences, Radiology, Uppsala University, Uppsala, SwedenDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden;Department of Imaging and Function, Skåne University Healthcare, Lund, SwedenOther articles by this author:;Department of Immunology, Genetics and Pathology, Section of pathology, Uppsala University Hospital and Uppsala University, Uppsala, SwedenOther articles by this author:;Department of Neuroscience, Neurology, Uppsala University, Uppsala, SwedenOther articles by this author:;Department of Neuroscience, Neurosurgery, Uppsala University, Uppsala, SwedenOther articles by this author:;Department of Surgical Sciences, Radiology, Uppsala University, Uppsala, SwedenOther articles by this author:

关键词: diffusion kurtosis imaging (DKI);    glioma;    perilesional;    tumor infiltration;    grade;    subtype;   

DOI  :  10.1515/raon-2017-0010

学科分类：肿瘤学

来源: Onkoloski Institut Ljubljana / Institute of Oncology Ljubljana

【 摘 要 】

BackgroundDiffusion kurtosis imaging (DKI) allows for assessment of diffusion influenced by microcellular structures. We analyzed DKI in suspected low-grade gliomas prior to histopathological diagnosis. The aim was to investigate if diffusion parameters in the perilesional normal-appearing white matter (NAWM) differed from contralesional white matter, and to investigate differences between glioma malignancy grades II and III and glioma subtypes (astrocytomas and oligodendrogliomas).

【 授权许可】

Unknown