Recovery with a regular dose of antibiotics from bacillary hemoglobinuria ina Holstein cow

The Journal of Veterinary Medical Science

Moeko KOHYAMA¹  Osamu YAMATO¹  Tetsushi ONO²  Akira YABUKI²  Mitsuhiro TAKAGI²  Satoshi ADACHI³  Hidenori TAMURA³  Masayasu TANIGUCHI³  Daiji SHIRAO³ 

[1] Laboratory of Clinical Pathology, Joint Faculty ofVeterinary Medicine, Kagoshima University, 1–21–24 Kohrimoto, Kagoshima-shi, Kagoshima890–0065, Japan;Laboratory of Theriogenology, Joint Faculty ofVeterinary Medicine, Yamaguchi University, 1677–1 Yoshida, Yamaguchi-shi, Yamaguchi753–8511, Japan;Shimonoseki Livestock Clinic, NOSAI Yamaguchi, 6880–1Kawatana, Toyoura-cho, Yamaguchi 759–3112, Japan

关键词: bacillary hemoglobinuria;    Clostridium haemolyticum;    flagellin gene;    Holstein cattle;   

DOI  :  10.1292/jvms.16-0296

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

One Holstein cow housed with 21 other cows exhibited clinical signs of pyrexia, anorexiaand diarrhea along with severe hemoglobinuria. Hematological and biochemical analysesconducted before and after antibiotic therapy indicated severe hemolytic anemia anddisruption of hepatic function. A general improvement in conditions was observed after an11-day program of treatment comprising a regular dose of antibiotics and prescribedsupportive therapies. A tentative diagnosis of bacillary hemoglobinuria was made based onthe clinical and clinico-pathologic features on day 7. A molecular diagnosis was made by aPCR amplification of the flagellin gene of Clostridium haemolyticum usingDNA extracted from the whole blood. The cow was diagnosed with the first recordedoccurrence of bacillary hemoglobinuria of Holstein cattle in Japan.

【 授权许可】

Unknown