Cardiorespiratory dose-response relationship of isoflurane in Cinereous vulture (Aegypius monachus) during spontaneous ventilation

The Journal of Veterinary Medical Science

Hee-Chun LEE¹  Dong-Hyuk JEONG²  Seong-Chan YEON³  Seong-Hoon SEOK⁴  Il-Hwa HONG⁵ 

[1] Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea;GyeongNam Wildlife Center, Jinju, Republic of Korea;Laboratory of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea;Laboratory of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea;Species Restoration Technology Institute of Korea National Park Service, Gurye, Republic of Korea

关键词: Aegypius monachus;    anesthesia;    cardiorespiratory;    Cinereous vulture;    isoflurane;   

DOI  :  10.1292/jvms.16-0314

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Anesthesia is an inevitably important component of diagnosis and treatments examining the health condition of wild animals. Not only does anesthesia become an essential tool in minimizing stress of the patients and providing an opportunity to deliver accurate and safe procedures, but it also ensures the safety of the medical crew members. This study was conducted to investigate the dose-response cardiorespiratory effects of isoflurane during spontaneous ventilation in ten cinereous vultures. Each bird was administered isoflurane at initial concentration of 1.0, 1.5, 2.0, 2.5 and 3.0 and then an end-tidal isoflurane concentrations (ETiso) of 1.0% for an equilibration period of 15 min in the given order. At the end of the equilibration period, the direct blood pressure (BP), heart rate (HR), respiratory rate (RR) and end tidal CO2 partial pressure (PETCO2) were recorded, and blood gas analysis was performed. Increasing isoflurane concentrations during spontaneous ventilation led to dose-dependent increases in HR and PETCO2, with minimal changes in RR, decreased arterial BP and respiratory acidosis. Overall, isoflurane for anesthesia of spontaneously breathing cinereous vultures is a suitable choice for diagnostic or surgical procedures.

【 授权许可】

Unknown