TFE3, HSP47, and CREB3 Pathways of the Mammalian Golgi Stress Response

Cell Structure and Function

Mai Taniguchi¹  Hiderou Yoshida¹ 

[1] Department of Molecular Biochemistry, Graduate School of Life Science, University of Hyogo

关键词: TFE3;    MLX;    HSP47;    CREB3;    organelle autoregulation;   

DOI  :  10.1247/csf.16023

学科分类：分子生物学，细胞生物学和基因

来源: Japan Society for Cell Biology

【 摘 要 】

The capacity of each organelle in eukaryotic cells is tightly regulated in accordance with cellular demands by specific regulatory systems, which are generically termed organelle autoregulation. The Golgi stress response is one of the systems of organelle autoregulation and it augments the capacity of Golgi function if this becomes insufficient (Golgi stress). Recently, several pathways of the mammalian Golgi stress response have been identified, specifically the TFE3, HSP47, and CREB3 pathways. This review summarizes the essential parts of the Golgi stress response from the perspective of the organelle autoregulation.

【 授权许可】

Unknown