Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses

The Journal of Veterinary Medical Science

Koichi FURUSAKI¹  Rumiko ONISHI¹  Rikio KIRISAWA²  Maho OSAKI²  Takashi ONODERA³  Ryuji NAKASHIMA⁴  Shigeru MIYAZAKI⁴  Masaomi KAWAMOTO⁴  Akikazu SAKUDO⁵ 

[1] Mineral Activation Technical Research Center, Omuta, Fukuoka 836-0041, Japan;Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan;Research Center for Food Safety, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan;Research Institute for Animal Science in Biochemistry and Toxicology, Midori-ku, Sagamihara, Kanagawa 252-0132, Japan;University of the Ryukyus, Nishihara, Okinawa 903-0215, Japan

关键词: antisepsis;    biosecurity;    calcium hydrogen carbonate;    influenza virus;    public health;   

DOI  :  10.1292/jvms.16-0603

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment.

【 授权许可】

Unknown