Enzymatically promoted release of organic molecules linked to magnetic nanoparticles

Beilstein Journal of Nanotechnology

关键词: drug delivery;    enzyme catalysis;    magnetic nanoparticles;    magnetic properties;    peptides;   

DOI  :  10.3762/bjnano.9.92

学科分类：地球科学(综合)

来源: Beilstein - Institut zur Foerderung der Chemischen Wissenschaften

【 摘 要 】

Magnetite-based magnetic nanoparticles have been successfully coupled to an organic system constituted of a fluorescent molecule, a tripeptide specifier and a spacer. The system is able to selectively release the fluorescent molecule upon targeted enzymatic hydrolysis promoted by a lysine/arginine specific protease.

【 授权许可】

CC BY