Relationship between indirect blood pressure and various stages of chronic kidney disease in cats

The Journal of Veterinary Medical Science

Atsushi HIRAKAWA¹  Noriko ISAYAMA²  Yohei YAMASHITA³  Toshiki IBARAGI⁴  Akihito KITADE⁵  Tamotsu SAWADA⁶  Hideyuki ONODERA⁷  Yoshitaka ARAMAKI⁸  Masayuki IGUCHI⁹  Shigeki YAMANO^1,10  Yasuhiro HEISHIMA^1,11  Yasutomo HORI^1,11  Michio KATAGI^1,12  Nobuyuki KANNO^1,13  Kensuke NAKAMURA^1,14 

[1] Bay Veterinary Hospital, 5-6-7 Ujinanishi, Minami, Hiroshima, Hiroshima 734-0014, Japan;Ebisu Animal Hospital, 3-3-43 Nishitaga, Taihaku, Sendai, Miyagi 982-0034, Japan;Heisei Animal Hospital, 2-1-1 Futago-cho, Kasugai, Aichi 486-0955, Japan;Iguchi Animal Hospital, 6-2-34 Kamijima, Naka, Hamamatsu, Shizuoka 433-8122, Japan;Katagi Animal Hospital, 565-5 Matoba, Kawagoe, Saitama 350-1101, Japan;Kitade Animal Hospital, 2 Ichishichotajiri, Tsu, Mie 515-2516, Japan;Miyoshi Inter Animal Hospital, 27-103 Neura Fukuya-cho, Miyoshi, Aichi 470-0217, Japan;Onodera Animal Hospital, 1-10-4 Chuou, Rifu-cho, Miyagi, Miyagi 981-0104, Japan;Organization for Promotion of Tenure Track, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192 Japan;Pet Clinic Hallelujah, 2544-1 Nakabaru, Kasuya-machi, Kasuya, Fukuoka 811-2304, Japan;School of Veterinary Medicine, Rakuno Gakuen University, 582 Midori-machi, Bunkyodai, Ebetsu, Hokkaido 069-8501, Japan;Ueda Animal Clinic, 2-202 Ueda, Tenpaku, Nagoya, Aichi 465-0081, Japan;Uenonomori Animal Clinic, 1-5-11 Yanaka Taito, Tokyo 110-0001, Japan;Veterinary Internal Medicine, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-8510, Japan

关键词: blood pressure;    cat;    chronic kidney disease;    hypertension;    oscillometry;   

DOI  :  10.1292/jvms.17-0620

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Chronic kidney disease (CKD) is a common cause of secondary systemic hypertension in cats. We investigated the relationship between indirect blood pressure and the prevalence of systemic hypertension in various CKDstages in cats. Client-owned cats (24 control cats and 77 cats with CKD) were included. Biochemical examinations of plasma were conducted by a commercial laboratory. Diseased cats were divided into two groups based onthe International Renal Interest Society (IRIS) guidelines (II and III–IV). Indirect blood pressure was measured using an oscillometric technique. Severe hypertension was diagnosed if systolic blood pressure (SBP) was≥180 mmHg. Indirect blood pressures were significantly higher in IRIS stage III–IV than in the control cats. Of 77 cats with CKD, 25 (32.5%) had severe hypertension. The frequency of severe hypertension increased with anincrease in IRIS stage; 0% in the controls, 27.6% in the IRIS stage II, and 47.4% in the IRIS stage III–IV, respectively. The indirect SBP was weakly correlated with urea nitrogen (r=0.27) and creatinine(r=0.23) concentrations in plasma. Binary logistic regression analysis showed that if plasma creatinine concentration is >3.7 mg/dl, cats with CKD had an increased risk fordeveloping severe hypertension (P<0.001). Our results suggest that indirect blood pressure was correlated with the severity of CKD, and the prevalence of severe hypertension increased in cats withsevere CKD. The risk of severe hypertension may be high in cats with severe CKD.

【 授权许可】

Unknown