Changes in serum NGF levels after the exercise load in dogs: a pilotstudy

The Journal of Veterinary Medical Science

Kaoru KARASAWA¹  Akane TANAKA¹  Izumi ANDO¹  Hiroshi MATSUDA² 

[1] Cooperative Major in Advanced Health Science, GraduateSchool of Bio-Applications and System Engineering, Tokyo University of Agriculture andTechnology, Tokyo 183–8509, Japan;Laboratory of Comparative Animal Medicine, Division ofAnimal Life Science, Institute of Agriculture, Tokyo University of Agriculture andTechnology, Tokyo 183–8509, Japan

关键词: cortisol;    dog;    external load;    nerve growth factor (NGF);    serum level;   

DOI  :  10.1292/jvms.16-0258

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Serum nerve growth factor (NGF) levels are increased by the external stress in mice,humans and horses; however, similar variations have been unclear in dogs. Since dogs areusually subjected to conditions of work, exercise and activity as important partners ofhumans, we measured serum NGF levels post-exercise and compared them with serum cortisollevels, as a biomarker of physical stress. Serum cortisol levels were immediately elevatedpost-exercise and returned to basal levels within 1 hr. On the other hand, serum NGFlevels were significantly increased 1 hr post-exercise and gradually returned to basallevels. Further research is necessary; nevertheless, we have demonstrated for the firsttime that serum NGF levels respond to exercise stress in dogs.

【 授权许可】

Unknown