Evolutionarily conserved morphogenetic movements at the vertebrate head–trunk interface coordinate the transport and assembly of hypopharyngeal structures

Developmental biology

CorinneLours-Calet¹ 

关键词: Evolution of vertebrate developmental mechanisms;    Head–trunk interface;    Morphogenetic movements;    Occipital lateral mesoderm;    Occipital somites;    Occipital ectoderm;    Occipital neural crest;    Hypobranchial/hypoglossal muscle;    Migratory muscle precursors;    Floor of pharynx;    Pharyngeal arches;    Circumpharyngeal route;    Zebrafish;    Xenopus;    Chicken;    Mouse;   

DOI  :  10.1016/j.ydbio.2014.03.003

学科分类：生物科学（综合）

来源: Academic Press

【 摘 要 】

The vertebrate head–trunk interface (occipital region) has been heavily remodelled during evolution, and its development is still poorly understood. In extant jawed vertebrates, this region provides muscle precursors for the throat and tongue (hypopharyngeal/hypobranchial/hypoglossal muscle precursors, HMP) that take a stereotype path rostrally along the pharynx and are thought to reach their target sites via active migration. Yet, this projection pattern emerged in jawless vertebrates before the evolution of migratory muscle precursors. This suggests that a so far elusive, more basic transport mechanism must have existed and may still be traceable today.

【 授权许可】

CC BY