A Simple, Efficient, Catalyst-Free and Solvent-Less Microwave-Assisted Process for N-Cbz Protection of Several Amines

Journal of the Korean Chemical Society

ABSTRACT A simple¹ 

关键词: Amine;    Benzyl chloroformate (Cbz-Cl);    Protection;    Microwave-assisted;    Solvent-free;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A simple, green and chemo-selective method for the N-benzyloxycarbonylation of amines, β-amino alcohols, α- amino esters and sulfonamides has been developed under microwave irradiation. Good to excellent yields of the N-benzyloxycarbamates compounds were obtained in short times without any side products.

【 授权许可】

Unknown