Thyroid cancer incidence in women and proximity to industrial air pollution sources: A spatial analysis in a middle size city in Colombia

Atmospheric Pollution Research

N.E.Arias-Ortiz¹ 

关键词: Endocrine disruptors;    Air pollution;    Industrial pollution;    Small-areas;    Bayesian modeling;    Disease clusters;   

DOI  :  10.1016/j.apr.2017.11.003

学科分类：农业科学（综合）

来源: Dokuz Eylul Universitesi * Department of Environmental Engineering

【 摘 要 】

Manizales, a mid-size city in Colombia, hosts industries like metallurgy, electrical, chemical, and rubber and plastic industrial facilities that have released into atmosphere some pollutants postulated as thyroid cancer (TC) promoters, such as dioxins and furans, dichloromethane, lead and copper. In this article we aim to detect clusters of TC and analyze their spatial association with industrial pollution. TC cases (2003–2010) were obtained from Manizales' Population-based Cancer Registry (PCR-Mz). Atmospheric emissions from industries were obtained from official reports of environmental authority. Data was spatially aggregated into census tracts and analyzed with Bayesian Besag-York and Mollié (BYM) models. Three exposure approaches were used: i) presence or absence of industries into census tracts, ii) sum of air discharges, and iii) an exposure index (EI) that considered the distance and orientation of the census tract regard to industries, average wind direction and speed, and population mobility. Models were fitted by exposure definition and sex, and included traffic and socioeconomic variables for adjustment. Using the Kulldorff's spatial exploration statistic we also performed point-data analyses in order to detect and localize clusters with individual data.

【 授权许可】

CC BY