Pituitary adenoma in monozigotic twins with Cri du Chat syndome: a rare case report

Romanian Neurosurgery

Gokhan Canaz¹  Huseyin Canaz²  Ibrahim Alatas² 

[1] Corresponding authorBakirkoy Research and Training Hospital for Neurology, Neurosurgery and Psychiatry, Department of Neurosurgery, Istanbul, Turkey;Florence Nightingale Hospital, Istanbul Bilim University, Department of Neurosurgery, Istanbul, TurkeyOther articles by this author:

关键词: pituitary;    Cri du Chat;    twins;    adenoma;   

DOI  :  10.1515/romneu-2016-0086

学科分类：精神健康和精神病学

来源: Romanian Society of Neurosurgery

【 摘 要 】

Pituitary adenomas are rare tumours of pediatric population. In etiology, genetic factors are more common than they are in adults. Because of the rarity of the cases, there are only a few large case studies in the literature. Pituitary tumours in children are often related with syndromes like MEN type 1, Carney Complex and Mc Cune Albright, but there is no case in the literature associated with Cri Du Chat syndrome. Statisticlly, it has been reported that, pediatric tumours occur more often in twins, in the pediatric population. Main treatment for prolactinomas is medical intervention with dopamine agonists, as in adults. Surgery is prefered when the tumour is resistant to medical treatment or shows mass effects around sellae. In that situation, as in adults, both transcranial and transsphenoidal approach is possible.

【 授权许可】

Unknown