Prognostic significance of uPA/PAI-1 level, HER2 status, and traditional histologic factors for survival in node-negative breast cancer patients

Radiology and Oncology

Nina Fokter Dovnik¹  Iztok Takac² 

[1] Corresponding authorMaribor University Clinical Center, Maribor, Slovenia;Maribor University Clinical Center, Maribor, SloveniaFaculty of Medicine, University of Maribor, Maribor, SloveniaOther articles by this author:

关键词: node-negative breast cancer;    adjuvant systemic treatment;    survival;    uPA/PAI-1;    HER2 status;   

DOI  :  10.1515/raon-2016-0024

学科分类：肿瘤学

来源: Onkoloski Institut Ljubljana / Institute of Oncology Ljubljana

【 摘 要 】

BackgroundThe association of HER2 status with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor 1 (PAI-1) levels raises the question whether uPA/PAI-1 level carries additional clinically relevant prognostic information independently from HER2 status. The aim of our study was to compare the prognostic value of uPA/PAI-1 level, HER2 status, and traditional prognostic factors for survival in node-negative breast cancer patients.

【 授权许可】

Unknown