Serum 25-hydroxyvitamin D concentrations in dogs with suspected acutepancreatitis

The Journal of Veterinary Medical Science

Byeong-Teck KANG¹  Ji-Houn KANG¹  Mhan-Pyo YANG¹  Hakhyun KIM¹  Dong-In KIM¹  Purum SON¹ 

[1] College of Veterinary Medicine and Veterinary MedicalCenter, Chungbuk National University, Cheongju, Chungbuk 28644, Republic ofKorea

关键词: canine;    C-reactive protein;    hypocalcemia;    inflammation;    vitamin D;   

DOI  :  10.1292/jvms.16-0647

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

The present study aimed to determine whether circulating serum concentrations of25-hydroxyvitamin D [25-(OH) D] differed between healthy dogs and dogs with acutepancreatitis (AP). Twenty-two healthy dogs and twenty client-owned dogs with AP wereenrolled in the study. Serum concentrations of 25-(OH) D, blood ionized calcium (iCa), andserum C-reactive protein (CRP) were measured. Concentrations of serum 25-(OH) D and bloodiCa in dogs with AP were significantly lower than those of healthy dogs, and serumconcentrations of CRP in dogs with AP were significantly higher than those of healthydogs. A significant difference in 25-(OH) D serum concentrations was observed betweensurvivor and non-survivor dogs with AP. After resolution of clinical signs, concentrationsof serum 25-(OH) D, blood iCa, and serum CRP did not differ compared to those beforetreatment. This study shows that dogs with AP exhibit decreased 25-(OH) D levels, whichmight be associated with calcium imbalances and mortality rate in canine AP.

【 授权许可】

Unknown