Myths in Modern Science: The Hydrogen Bond and its Surroundings Part 2. The Hydrophobic-Bond-Myth

Chem-Bio Informatics Journal

Motohiro Nishio¹ 

[1] The CHPI Institute

关键词: タンパク質;    疎水結合;    非極性側鎖;    ギブス自由エネルギー;    proteins;    hydrogen bond;    nonpolar side-chain;    Gibbs free energy;   

DOI  :  10.1273/cbij.18.10

学科分类：生物化学/生物物理

来源: Chem-Bio Informatics Society

【 摘 要 】

The fashionable but stereotypic thinking on the concept of the so-called “hydrophobic bond” has been examined in light of criticisms raised by many scientists Hildebrand, Shinoda, Israelachvili, and so on. The author's comments are given on the harmful influence of the concept of “hydrophobic bond” in chemistry and biochemistry. In my opinion, this concept can be considered as a myth in modern science.

【 授权许可】

CC BY